Hazel Wu

PhD student

Education:

B.Sc in Animal and Plant Biotechnology, The University of Hong Kong, HK

M.Sc in Plant Breeding and Biotechnology, University of East Anglia, UK

Research project:

Antigenic profiling of H5N1 viruses

Publications:

Wu, W. L., Y. Chen, P. Wang, W. Song, S.-Y. Lau, J. M. Rayner, G. J. D. Smith, R. G. Webster, J. S. M. Peiris, T. Lin, N. Xia, Y. Guan, and H. Chen. 2008. Antigenic Profile of Avian H5N1 Viruses in Asia from 2002 to 2007. J. Virol. 82:1798-1807.

Duan, L., L. Campitelli, X. H. Fan, Y. H. Leung, D. Vijaykrishna, J. X. Zhang, I. Donatelli, M. Delogu, K. S. Li, E. Foni, C. Chiapponi, W. L. Wu, H. Kai, R. G. Webster, K. F. Shortridge, J. S. Peiris, G. J. Smith, H. Chen, and Y. Guan. 2007. Characterization of low-pathogenic H5 subtype influenza viruses from Eurasia: implications for the origin of highly pathogenic H5N1 viruses. J Virol 81:7529-39.

Chen, H., G. J. Smith, K. S. Li, J. Wang, X. H. Fan, J. M. Rayner, D. Vijaykrishna, J. X. Zhang, L. J. Zhang, C. T. Guo, C. L. Cheung, K. M. Xu, L. Duan, K. Huang, K. Qin, Y. H. Leung, W. L. Wu, H. R. Lu, Y. Chen, N. S. Xia, T. S. Naipospos, K. Y. Yuen, S. S. Hassan, S. Bahri, T. D. Nguyen, R. G. Webster, J. S. Peiris, and Y. Guan. 2006. Establishment of multiple sublineages of H5N1 influenza virus in Asia: implications for pandemic control. Proc Natl Acad Sci U S A 103:2845-50.


Qin Kun

PhD student

Education:

2000-2005: DVM, College of Veterinary Medicine, China Agricultural Univ. PR.China

2005-Present: Dept of Microbiology, HKU, HK SAR. PR.China

Research interest:

epidemiology of swine influenza viruses in China and pathogencity of avian influenza viruses in different hosts.

Publications:

Smith GJ, Fan XH, Wang J, Li KS, Qin K, Zhang JX, Vijaykrishna D, Cheung CL, Huang K, Rayner JM, Peiris JMS, Chen H, Webster RG, Guan Y (2006), Emergence and predominance of an H5N1 influeza variant in China, PNAS, 103: 16936 16941.

Chen H, Smith GJD, Li KS, Wang J, Fan XF, Rayner JM, Zhang J, Vijaykrishna D, Guo CT, Cheung CL, Xu KM, Duan L, Huang K, Qin K, Leung YHC, Wu WH, Lu HR, Chen Y, Xiao NS, Naipospos TSP, Hassan SS, Nguyen TD, Zhang LJ, Yuen KY, Webster RG, Peiris JSM, Guan Y (2006), Establishment of multiple sub-lineages of H5N1 influenza virus in Asia implications for pandemic control. PNAS, 103: 2845-2850.

Liu J, Xiao H, Lei F, Zhu Q, Qin K, Zhang XW, Zhang XL, Zhao D, Wang G, Feng Y, Ma J, Liu W, Wang J, Gao GF (2005). Highly pathogenic H5N1 influenza virus infection in migratory birds, Science. 19; 309(5738):120



Wang Jia

PhD student




Wang Pui

PhD student





William Cheung

PhD student / Senior Research Assistant

Research:

My research focus is on the epidemiology of H6 subtype influenza viruses in southern China. Through our systematic surveillance data in southern China, we suggested that H6N1 influenza viruses have become established and endemic in minor poultry species. Reassortment of internal genes between different subtype of viruses like H5N1, H9N2 and other avian influenza viruses, generated multiple novel H6N1 viruses circulating in poultry in southern China. These results suggested that the markets in southern China were generating the genetic diversity of influenza viruses.

Publications

Cheung CL, Vijaykrishna D, Smith GJD, Fan XH, Zhang JX, Bahl J, Duan L, Huang K, Tai H, Wang J, Poon LL, Peiris JS, Chen H, Guan Y. Establishment of influenza A virus (H6N1) in minor poultry species in southern China. Journal of Virology. 2007 Oct;81(19):10402-12.

Smith GJD, Fan XH, Wang J, Li KS, Qin K, Zhang JX, Vijaykrishna, D, Cheung CL, Huang K, Rayner JM, Peiris JSM, Chen H, Webster RG, Guan Y. Emergence and predominance of an H5N1 influenza variant in China. Proceedings of the National Academy of Sciences. 2006 Nov 7; 103(45):16936-41.

Tang XC, Zhang JX, Zhang SY, Wang P, Fan XH, Li LF, Li G, Dong BQ, Liu W, Cheung CL, Xu KM, Song WJ, Vijaykrishna D, Poon LL, Peiris JS, Smith GJD, Chen H, Guan Y. Prevalence and genetic diversity of coronaviruses in bats from China. Journal of Virology. 2006 Aug; 80(15):7481-90.

Smith GJD, Naipospos TS, Nguyen TD, de Jong MD, Vijaykrishna D, Usman TB, Hassan SS, Nguyen TV, Dao TV, Bui NA, Leung YH, Cheung CL, Rayner JM, Zhang JX, Zhang LJ, Poon LL, Li KS, Nguyen VC, Hien TT, Farrar J, Webster RG, Chen H, Peiris JS, Guan Y. Evolution and adaptation of H5N1 influenza virus in avian and human hosts in Indonesia and Vietnam. Virology. 2006 Jul 5; 350(2):258-68.

Cheung CL, Rayner JM, Smith GJD, Wang P, Naipospos TS, Zhang J, Yuen KY, Webster RG, Peiris JS, Guan Y, Chen H. Distribution of amantadine-resistant H5N1 avian influenza variants in Asia. Journal of Infectious Diseases. 2006 Jun 15; 193(12):1626-9.

Chen H, Smith GJD, Li KS, Wang J, Fan XH, Rayner JM, Vijaykrishna D, Zhang JX, Zhang LJ, Guo CT, Cheung CL, Xu KM, Duan L, Huang K, Qin K, Leung YH, Wu WL, Lu HR, Chen Y, Xia NS, Naipospos TS, Yuen KY, Hassan SS, Bahri S, Nguyen TD, Webster RG, Peiris JS, Guan Y. Establishment of multiple sublineages of H5N1 influenza virus in Asia: implications for pandemic control. Proceedings of the National Academy of Sciences U S A. 2006 Feb 21; 103(8):2845-50.

Guan Y, Poon LL, Cheung CY, Ellis TM, Lim W, Lipatov AS, Chan KH, Sturm-Ramirez KM, Cheung CL, Leung YH, Yuen KY, Webster RG, Peiris JS. H5N1 influenza: a protean pandemic threat. Proceedings of the National Academy of Sciences U S A. 2004 May 25; 101(21): 8156-61.

Guan Y, Zheng BJ, He YQ, Liu XL, Zhuang ZX, Cheung CL, Luo SW, Li PH, Zhang LJ, Guan YJ, Butt KM, Wong KL, Chan KW, Lim W, Shortridge KF, Yuen KY, Peiris JS, Poon LL. Isolation and characterization of viruses related to the SARS Coronavirus from animals in Southern China. Science. 2003 Oct 10; 302(5643):276-8.


Huang Kai

PhD student

Selected publications:

Chen, H., Smith, G. J., Li, K. S., Wang, J., Fan, X. H., Rayner, J. M., et al. (2006). Establishment of multiple sublineages of H5N1 influenza virus in Asia: implications for pandemic control. Proc Natl Acad Sci U S A, 103(8), 2845-2850.

Cheung, C. L., Vijaykrishna, D., Smith, G. J., Fan, X. H., Zhang, J. X., Bahl, J., et al. (2007). Establishment of influenza A virus (H6N1) in minor poultry species in southern China. J Virol, 81(19), 10402-10412.

Duan, L., Campitelli, L., Fan, X. H., Leung, Y. H., Vijaykrishna, D., Zhang, J. X., et al. (2007). Characterization of low-pathogenic H5 subtype influenza viruses from Eurasia: implications for the origin of highly pathogenic H5N1 viruses. J Virol, 81(14), 7529-7539.

Smith, G. J., Fan, X. H., Wang, J., Li, K. S., Qin, K., Zhang, J. X., et al. (2006). Emergence and predominance of an H5N1 influenza variant in China. Proc Natl Acad Sci U S A, 103(45), 16936-16941.


Duan Lian

PhD student