Organization
Project Coordinator and Director
Malik Perris
Management Board
AoE Coordinator: JSM Peiris
Group leaders: Y Guan, YL Lau, N Ip, GM Leung, KY Yuen, PK Chan, HL Chen, LM Poon
External member: W Lim (Centre for Health Protection)
Scientific Advisory Board
Sir Roy Anderson, Peter C Doherty, Siamon Gordon, Edward C Holmes, Ab. DME Osterhaus and Sir John Skehel
AoE Themes
Theme 1. Ecology, evolution and inter-species transmission of influenza viruses
Leader: Yi Guan
Investigators: Gavin JD Smith, Honglin Chen, Malik Peiris
Theme 2: Pathogenesis, Host responses and innate immunity
Leaders: JSM Peiris, YL Lau, NY Ip
Investigators: H Chen, Y Guan, ASY Lau, S Lok, B Nal-Rogier, JM Nicholls, HB Peng, LLM Poon, SW Tsao, W Tu, TM Wong, KY Yuen
Theme 3: Epidemiology, field studies and modeling of human and animal influenza
Leader: GM Leung
Investigators: SSS Chiu, BJ Cowling, Y Guan, JSM Peiris, S Riley, CM Wong, TW Wong, JT Wu
Theme 4: Clinical studies, diagnostics and therapeutics
Leaders: KY Yuen, PK Chan
Investigators: H Chen, CM Chu, SSS Chiu, Y Guan, H Hui, RYT Kao, NY Ip, ASY Lau, YL Lau, B Nal-Rogier, LLM Poon, JSM Peiris, W Tu
Collaborators: HC Lee, CM Che, J Karlberg, PM Vanhoutte.
Theme 5: Antiviral immunity and vaccine development for control of human and animal infection
Leaders: H Chen, LLM Poon
Investigators: BJ Zheng, KY Yuen, JD Huang, Y Guan, YL Lau, W Tu
Names and Academic Affiliations of Research Collaborators
Research Collaborators: Hong Kong & mainland China | |
| R Bruzzone, CEO, HKU-Pasteur Research Centre | Coordinator, RESPARI Network of Pasteur labs in Asia |
| KH Chan, Microbiology, Queen Mary Hospital | Laboratory diagnosis of influenza |
| CM Che, Dept of Chemistry, HKU and Institute of Molecular Technology for Drug | Medicinal chemistry and drug discovery |
| Discovery and Synthesis | |
| X Che, Nanfong University of Guangzhou | Development of rapid diagnostic tests for influenza |
| CM Chu, United Christian Hospital, Hospital Authority | Respiratory Medicine |
| KC Dyrting, Dept of Agriculture, Fisheries & Conservation | Animal influenza surveillance within Hong Kong |
| J Karlberg, Director, Clinical Trials Centre, HKU | Clinical trials |
| Co Jian, Guangdong No 12 Hospital | Multi-centre study on influenza epidemiology |
| KS Li, Dept of Microbiology, Shantou University | Key collaborator on influenza surveillance, Shantou |
| Yuan Qian, Laboratory of Virology, Capital Institute of Pediatrics, Beijing. | Collaborating on multi-centre study on influenza epidemiology |
| PM Vanhoutte, Biopharmaceutical Development Centre, HKU | Downstream pharmaceutical development (Previously Director of Discovery Research, Servier) |
| Ricky NS Wong, Department of Applied Biology, Hong Kong Baptist University | Effects of traditional Chinese herbs on cell biology and cell signaling |
| Y Wang, Director, Chinese Centre for Disease Control | Influenza epidemiology |
| Jian-ping Zhuo, Shanghai Institute of Materia Medica, Chinese Academy of Science | Small-molecule library of the SIMM for influenza drug screening. |
Research Collaborators: International | |
| S Akira, Osaka University | Innate immunity, Sensing receptors, cell signaling |
| Ann Arvin, Stanford University | Rag2-/- / Il2rg-/- “humanized” mice |
| AJ Leigh Brown, University of Edinburgh | Viral genomics of human H5N1 influenza infections |
| John Edwards, Murdoch University, Australia | Veterinary epidemiology and surveillance |
| ATS Estoepangestie, Airlangga University, Indonesia | Avian influenza surveillance |
| NM Ferguson, Imperial College, London | Mathematical modeling of infectious diseases |
| J Farrar, Hospital for Tropical Diseases, Ho Chi Minh City and University of Oxford. | Clinical and laboratory aspects of human H5N1 disease. Coordinator of a multicentre NIAID study on human H5N1 |
| J Goudsmit, Chief Scientific Officer, Crucell | Advise on the Science-Industry interface |
| Alan Hay, WHO Influenza Collaborating Centre, London | Global collaboration on influenza evolution , antigenic change, influenza vaccine strain selection |
| Stuart Haslam, Imperial College, London | Glycobiology |
| M von Itzstein, Institute for Glycomics, Griffith University, Queensland | Glycobiology (discoverer of the Flu-neuraminidase inhibitor Relenza) |
| Anne Kelso, Director, WHO Influenza Collaborating Centre, Melbourne | Global collaboration on influenza evolution , antigenic change, influenza vaccine strain selection |
| M Lipsitch, Harvard School of Public Health | Mathematical modeling; a PI on the NIH MIDAS project |
| S Ma, Ministry of Health, Singapore | Multi-centre study on influenza epidemiology |
| RJ Mason, National & Jewish Medical Research Center, Denver | Primary human type 1 / type 2 lung epithelial cell cultures in-vitro |
| Prof RS Morris, Massey University, New-Zealand | Veterinary epidemiology |
| TSP Naipospos, CIVAS, Jakarta | Avian influenza surveillance |
| ND Nguyen, National Institute of Veterinary Research, Hanoi, Vietnam | Avian influenza surveillance |
| A Rambaut, University of Edinburgh | Evolution and population dynamics of influenza viruses |
| K Takahashi, Harvard Medical School | Provide MBL-knockout mice |
| Dr M Uiprasertkul, Mahidol University, Thailand | Pathology of human H5N1 disease |
| Dr RG Webster, WHO Influenza Collaborating Center, Memphis | Key collaborative partner on past research activities and on current NIAID “Centers of Excellence for Influenza Research and Surveillance” research contract (2007-2013) |
| Xiaowei Zhuang, Howard Hughes Medical Institute, Harvard | Single virus particle tracking experiments in cells |